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Our PUBLICATIONS

journal articles

10TOTAL RESOURCES
B. Liefers, P. Taylor, A. Alsaedi, C. Bailey, K. Balaskas, N. Dhingra, C. A. Egan, F. G. Rodrigues, C. González-Gonzalo, T. F. C. Heeren, A. Lotery, P. L. Muller, A. Olvera-Barrios, B. Paul, R. Schwartz, D. S. Thomas, A. N. Warwick, A. Tufail and C. I. Sánchez, "Quantification of key retinal features in early and late age-related macular degeneration using deep learning", American Journal of Ophthalmology, 2021.
B. Liefers, J. M. Colijn, C. González-Gonzalo, T. Verzijden, J. J. Wang, N. Joachim, P. Mitchell, C. B. Hoyng, B. van Ginneken, C. C. Klaver and C. I. Sánchez, "A deep learning model for segmentation of geographic atrophy to study its long-term natural history", Ophthalmology, 2020; 127 (8): 1086-1096.
C. González-Gonzalo, B. Liefers, B. van Ginneken and C. I. Sánchez, "Iterative augmentation of visual evidence for weakly-supervised lesion localization in deep interpretability frameworks: application to color fundus images", IEEE Transactions on Medical Imaging, 2020; 39 (11): 3499-3511.
V. Schreur, A. Domanian, B. Liefers, F. G. Venhuizen, B. J. Klevering, C. B. Hoyng, E. K. de Jong and T. Theelen, "Morphological and topographical appearance of microaneurysms on optical coherence tomography angiography", British Journal of Ophthalmology, 2019; 103 (5): 630-635.
D. Valkenburg, E. H. Runhart, N. M. Bax, B. Liefers, S. L. Lambertus, C. I. Sánchez, F. P. Cremers and C. B. Hoyng, "Highly variable disease courses in siblings with Stargardt disease", Ophthalmology, 2019; 126: 1712-1721.
T. J. Heesterbeek, E. K. de Jong, I. E. Acar, J. M. M. Groenewoud, B. Liefers, C. I. Sánchez, T. Peto, C. B. Hoyng, D. Pauleikhoff, H. W. Hense and A. I. den Hollander, "Genetic risk score has added value over initial clinical grading stage in predicting disease progression in age-related macular degeneration", Nature Scientific Reports, 2019; 9: 6611.
J. J. Gómez-Valverde, A. Antón, G. Fatti, B. Liefers, A. Herranz, A. Santos, C. I. Sánchez and M. J. Ledesma-Carbayo, "Automatic glaucoma classification using color fundus images based on convolutional neural networks and transfer learning", Biomedical Optics Express, 2019; 10 (2): 892-913.
F. G. Venhuizen, B. van Ginneken, B. Liefers, F. van Asten, V. Schreur, S. Fauser, C. B. Hoyng, T. Theelen and C. I. Sánchez, "A Deep Learning Approach for Detection and Quantification of Intraretinal Cystoid Fluid in Multivendor Optical Coherence Tomography", Biomedical Optics Express, 2018; 9 (4): 1545-1569.
F. G. Venhuizen, B. van Ginneken, B. Liefers, Schreur, M. J. van Grinsven, S. Fauser, C. B. Hoyng, T. Theelen and C. I. Sánchez, "Robust Total Retina Thickness Segmentation in Optical Coherence Tomography Images using Convolutional Neural Networks", Biomedical Optics Express, 2017; 8 (7): 3292-3316.
B. Liefers, F. G. Venhuizen, V. Schreur, B. van Ginneken, C. Hoyng, S. Fauser, T. Theelen and C. I. Sánchez, "Automatic detection of the foveal center in optical coherence tomography", Biomedical Optics Express, 2017; 8 (11): 5160-5178.

inproceedings

3TOTAL RESOURCES
B. Liefers, C. González-Gonzalo, C. Klaver, B. van Ginneken and C. I. Sánchez, "Dense Segmentation in Selected Dimensions: Application to Retinal Optical Coherence Tomography", Medical Imaging with Deep Learning, 2019; 102: 337-346.
C. González-Gonzalo, B. Liefers, B. van Ginneken and C. I. Sánchez, "Improving weakly-supervised lesion localization with iterative saliency map refinement", Medical Imaging with Deep Learning, 2018.
B. Liefers, F. G. Venhuizen, T. Theelen, C. Hoyng, B. van Ginneken and C. I. Sánchez, "Fovea Detection in Optical Coherence Tomography using Convolutional Neural Networks", Medical Imaging, 2017; 10133: 1013302.

abstracts

11TOTAL RESOURCES
C. González-Gonzalo, E. F. Thee, B. Liefers, C. W. Klaver and C. I. Sánchez, "Deep learning for automated stratification of ophthalmic images: Application to age-related macular degeneration and color fundus images", European Society of Retina Specialists, 2021.
C. González-Gonzalo, E. F. Thee, B. Liefers, C. de Vente, C. C. W. Klaver and C. I. Sánchez, "Hierarchical curriculum learning for robust automated detection of low-prevalence retinal disease features: application to reticular pseudodrusen", Association for Research in Vision and Ophthalmology, 2021.
C. González-Gonzalo, S. C. Wetstein, G. Bortsova, B. Liefers, B. van Ginneken and C. I. Sánchez, "Are adversarial attacks an actual threat for deep learning systems in real-world eye disease screening settings?", European Society of Retina Specialists, 2020.
A. Ardu, B. Liefers, C. de Vente, C. González-Gonzalo, C. Klaver and C. I. Sánchez, "Artificial Intelligence for the Classification and Quantification of Reticular Pseudodrusen in Multimodal Retinal Images", European Society of Retina Specialists, 2020.
D. Valkenburg, E. Runhart, B. Liefers, S. Lambertus, C. I. Sánchez, F. P. Cremers, B. Nathalie M and C. C. B. Hoyng, "Familial discordance in disease phenotype in siblings with Stargardt disease", Association for Research in Vision and Ophthalmology, 2019.
B. Liefers, J. Colijn, C. González-Gonzalo, A. Vaidyanathan, H. van Zeeland, P. Mitchell, C. Klaver and C. I. Sánchez, "Prediction of areas at risk of developing geographic atrophy in color fundus images using deep learning", Association for Research in Vision and Ophthalmology, 2019.
C. González-Gonzalo, B. Liefers, A. Vaidyanathan, H. van Zeeland, C. C. W. Klaver and C. I. Sánchez, "Opening the “black box”? of deep learning in automated screening of eye diseases", Association for Research in Vision and Ophthalmology, 2019.
F. G. Venhuizen, S. Schaffhauser, V. Schreur, B. Liefers, B. van Ginneken, C. B. Hoyng, T. Theelen, E. K. de Jong and C. I. Sánchez, "Fully automated detection of hyperreflective foci in optical coherence tomography", Association for Research in Vision and Ophthalmology, 2017.
B. Liefers, F. G. Venhuizen, V. Schreur, B. van Ginneken, C. Hoyng, T. Theelen and C. I. Sánchez, "Automatic detection of the foveal center in optical coherence tomography", Association for Research in Vision and Ophthalmology, 2017.
J. J. Gomez, C. I. Sánchez, B. Liefers, F. G. Venhuizen, G. Fatti, A. Morilla-Grasa, Y. Cartagena, A. H. Cabarcos, A. Santos, M. J. Ledesma-Carbayo and A. Anton-Lopez, "Automated Analysis of Retinal Images for detection of Glaucoma based on Convolutional Neural Networks", Association for Research in Vision and Ophthalmology, 2017.
B. Liefers, V. Schreur, T. Theelen and C. I. Sánchez, "Registration and grading of micro-aneurysms in Fluorescein Angiography and OCT Angiography", 4th International Congress on OCT Angiography and Advances in OCT, 2016.

preprint

4TOTAL RESOURCES
P. L. Muller, B. Liefers, T. Treis, F. Gomes Rodrigues, A. Olvera-Barrios, B. Paul, N. Dhingra, A. Lotery, C. Bailey, P. Taylor, C. I. Sánchez and A. Tufail, "Reliability of retinal pathology quantification in age-related macular degeneration: Implications for clinical trials and machine learning applications", 2020.
S. C. Wetstein, C. González-Gonzalo, G. Bortsova, B. Liefers, F. Dubost, I. Katramados, L. Hogeweg, B. van Ginneken, J. P. W. Pluim, M. de Bruijne, C. I. Sánchez and M. Veta, "Adversarial Attack Vulnerability of Medical Image Analysis Systems: Unexplored Factors", arXiv:200.606.356, 2020.
B. Liefers, J. M. Colijn, C. González-Gonzalo, T. Verzijden, P. Mitchell, C. B. Hoyng, B. van Ginneken, C. C. Klaver and C. I. Sánchez, "A deep learning model for segmentation of geographic atrophy to study its long-term natural history", arXiv:190.805.621, 2019.
C. González-Gonzalo, B. Liefers, B. van Ginneken and C. I. Sánchez, "Iterative augmentation of visual evidence for weakly-supervised lesion localization in deep interpretability frameworks", arXiv:191.007.373, 2019.